ERA® Endometrial Receptivity Analysis

The ERA® test helps avoid implantation failure by establishing the best day for embryo transfer

Overview

Many women undergoing IVF are unable to get pregnant, even after transferring good quality embryos. Although a good quality embryo is an important starting point, it is also important to transfer the embryo into a uterus that is ready to receive the embryo.

The timing of embryo transfer must coordinate with your body´s menstrual cycle, neither too early nor too late, but at just the right time. For most women, the best time to transfer an embryo is the same, but for some women, it can be different.

What is the endometrium?

The interior of the uterus is lined with a tissue called endometrium, which is prepared each month for the arrival of an embryo and it’s the nest where the embryo implants and resides during gestation.
Even the best embryo will fail to implant if conditions aren’t right.

What is Endometrial receptivity?

The endometrium is receptive when it is ready for embryo implantation to occur. This period of receptivity is called the window of implantation.
Each woman has a unique window. For some women the window is shorter and/or displaced. By knowing your personal window of implantation, you can optimize your chances of pregnancy through a personalized embryo transfer.

What is ERA test?

ERA® evaluates endometrial receptivity, the optimal time for embryo transfer that is specific for each woman.

*Simón et al., In vitro fertilization with personalized blastocyst transfer versus frozen or fresh blastocyst transfer: a multicenter, randomized clinical trial. Fertility and Sterility, 2019; 112. e56-e57. 10.1016/j.fertnstert.2019.07.273.

**Ruiz-Alonso et al., The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure. Fertility and Sterility, 2013;100(3):818-24. 10.1016/j.fertnstert.2013.05.004.

BROCHURE

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Why use ERA?

When performing the embryo transfer in a personalized way, the chances of getting pregnant are increased after the assisted reproduction treatment.
72.5%* pregnancy rate using ERA in the first IVF cycle in any patient.
Maximize your chances of pregnancy and don’t lose good embryos.
7 in 10 women gave birth after 1 year*.
Our recent randomized study* proves that a personalized embryo transfer is superior to the classic frozen embryo transfer.

Is ERA for you?

This test is recommended if:

Indicated for all patients starting assisted reproductive treatments, and has the greatest benefit for those who have experienced repeated implantation failures.

How does it work?

A RECEPTIVE RESULT
A receptive result shows that the window of implantation is ‘open’ at the time and day of taking the sample and the recommendation is to proceed with embryo transfer under the same conditions as the biopsy.
A NON – RECEPTIVE RESULT
A non-receptive result shows a displaced window of implantation. In this case, with the ERA computational predictor, we will estimate your window of implantation indicating when your personalized embryo transfer is optimal in 90% of the cases. A second biopsy will be needed in only 10% of cases.