Why should use SAT test?
An increase of sperm chromosomal abnormalities affects your reproductive journey at three levels:
- Spermatozoa with sex chromosome abnormalities results in aneuploid embryos
- Diploid sperm results in triploid embryos
Rodrigo et al., 2010.
- An altered SAT decreases pregnancy rate after ICSI and increases miscarriage rate
Rubio et al., 2001.
- Sperm chromosomal abnormalities increase the risk of abnormal offspring for the chromosomes affected in the sperm (Down, Klinefelter or Turner’s Syndromes)
Who should use SAT test?
- Men with a low sperm concentration, who typically have a higher incidence of sperm chromosome abnormalities
- Couples who have suffered recurrent miscarriage of unknown origin
- Couples who have experienced repeated implantation failure
- Couples with a previous pregnancy with a chromosomal abnormality
This technique allows the detection of aneuploidy only for the chromosomes included in the test (13, 18, 21, X and Y). In very few ejaculated samples or testicular samples, there is not enough spermatozoa for a proper estimation of the risk of aneuploidy.